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invasive  ·  ECoG ·  available

RNS System

By NeuroPace

Identity

Manufacturer
NeuroPace
Model number
RNS-320
Codename
Aliases
NeuroPace RNS, Responsive Neurostimulation System, RNS-300M
Generation
2nd-gen (RNS-320)
Country of origin
US
Released
Announced
Discontinued
Status
available

Classification

Invasiveness
invasive
Modalities
ECoG, sEEG, DBS
Primary modality
ECoG
Direction
read-write
Categories
medical-implant, therapeutic, stimulation, diagnostic
Form factor
cranial-implant
Use cases
responsive neurostimulation for medically refractory partial-onset seizures, chronic intracranial EEG recording at seizure foci
Target users
patient-epilepsy, neurologist, neurosurgeon

Electrodes

Total channels
8
Recording channels
8
Reference channels
Electrode type
depth-shaft, subdural-strip
Material
platinum-iridium
10-20 positions
Requires gel
Requires saline
Prep time
Reusable
No
Disposable
No

Signal acquisition

Sampling rate
250 Hz
ADC resolution
Notch filters
Onboard artifact rejection

Stimulation

Capable
Yes

Connectivity

Protocols
proprietary-inductive
Bluetooth
Bluetooth profiles
Concurrent mode
Encryption (transit)
Pairing methods
Cloud sync
Yes
Offline recording

Power

Sources
replaceable-other
Battery life (active)
Charging port
Charging time
Battery replaceable
No
Notes
Non-rechargeable. RNS-300M typical service life ~2.6–4.3 years; RNS-320 ~6.0–12.4 years with typical use. End-of-service requires surgical replacement of the cranial unit.

Physical

Weight
Dimensions
60 mm L × 28 mm W × 7.7 mm H
Materials
titanium, ceramic
Sizes
Head circumference
Operating temp

Compute

Has onboard computer
Yes
Operating systems
custom-firmware
Primary OS
custom-firmware
Edge ML accelerator
No
Root access
none
App sandbox
No
3rd-party apps allowed
No
Notes
On-device detection runs as fixed-function digital signal processing (line-length, area, half-wave, bandpass detectors). Not a general-purpose computing platform.

Software & data

Mobile app
Cloud platform
Yes
Offline mode
Subscription required
Raw data access
No
Export formats
LSL support
Data ownership
Apps

SDK & developer access

Has SDK
No
Open source
No
Languages
Web Bluetooth
Raw sample access
BCI paradigms
3rd-party integrations
Docs

Capabilities

Attention / focus
Meditation / calm
Neurofeedback
Meditation coaching
Sleep tracking

Security

Authentication factors
Per-user profiles
Requires account
Claiming methods
Ownership model
Activation lock
Remote lock
Remote wipe
Find my device
Notes

Firmware & updates

OTA supported
OTA transports
Update mechanism
Update channels
Rollback supported
Signed updates
Forced updates
User deferrable
Requires app companion
Average update frequency
Notes

Regulatory & clinical

FDA status
pma
CE mark
Certifications
Prescription required
Yes
Pediatric approved
No

Pricing & availability

MSRP
Current price
Subscription
Warranty
Return policy (days)
Where to buy

Media & links

Official site
neuropace.com
Product page
neuropace.com

Editor’s take

In favor

  • Only FDA-approved closed-loop responsive neurostimulator
  • Provides longitudinal ambulatory iEEG that no other device can
  • Skull-flush form factor avoids chest IPG and tunneled extensions

Against

  • Indication limited to 1–2 well-localized seizure foci
  • Non-rechargeable; surgical replacement required at end-of-service
  • No raw data access for patients or third parties

Sources & provenance

Last reviewed